Selected publications
2025
- Kutcher SA, Dendukuri N, Dandona S, Nadeau L, Brophy JM. Ticagrelor Compared to Clopidogrel in Acute Coronary Syndromes trial (TC4): a Bayesian pragmatic cluster randomized controlled trial. CMAJ 2025;197(12):E309-E318. DOI: 10.1503/cmaj.241862.
2024
Miceline Mésidor, Caroline Sirois, Jason Robert Guertin, Mireille E Schnitzer, Bernard Candas, Claudia Blais, Benoit Cossette, Paul Poirier, James M Brophy, Lisa Lix, Mina Tadrous, Awa Diop, Denis Hamel, Denis Talbot. Effect of statin use for the primary prevention of cardiovascular disease among older adults: A cautionary tale concerning target trials emulation. Journal of Clinical Epidemiology
James M Brophy Is science really self correcting? Something old and older. Medium.
Non peer review article based on a previous blog. Although I think this contains much interesting material, including the value of teaching,an exploration of immortal time bias, and its historical perspective, it was refused by > 6 (I lost count of exactly how many!) medical journals for “not meeting their priorities”.
2023
- James M Brophy. A Bayesian Perspective-Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest medRxiv, 2023.02. 13.23285890
2022
- Todd C Lee, Srinivas Murthy, Olivier Del Corpo, Julien Senécal, Guillaume Butler-Laporte, Zahra N Sohani, James M Brophy, Emily G McDonald. Remdesivir for the treatment of COVID-19: a systematic review and meta-analysis. Clinical Microbiology and Infection 28 (9), 1203-1210
2021
- James M Brophy. Bayesian analyses of cardiovascular trials—bringing added value to the table. Canadian Journal of Cardiology 37 (9), 1415-1427 2021
- James M Brophy. Key Issues in the Statistical Interpretation of Randomized Clinical Trials. Canadian Journal of Cardiology 37 (9), 1312-1321
2020
- James M Brophy. Bayesian interpretation of the EXCEL trial and other randomized clinical trials of left main coronary artery revascularization. JAMA Internal Medicine 180 (7), 986-992