Professor of Medicine & Epidemiology

McGill University

Biography

Jay Brophy is a tenured (full) professor with a joint appointment in the Departments of Medicine and Epidemiology and Biostatistics where he works as a clinical cardiologist and does research in cardiovascular epidemiology. His research interests are eclectic and include outcomes research, pharmacoepidemiology, health technology assessment, economic analyses and clinical research which are supported partially through a FRQS chair in health technology assessment and evidence-based medicine.
He is a fellow of the Canadian Academy of Health Sciences and the Canadian Cardiovascular Society.

Download my CV.

Interests
  • Outcomes research
  • Pharmacoepidemiology
  • Health technology assessment (Bayesian statistics)
Education

  • PhD Epidemiology & biostatistics

    McGill University

  • Cardiology

    Université de Montreal

  • MD

    McMaster University

  • M.Eng.

    McMaster University

  • B.Eng.

    McGill University

Skills

MD

33%

Epidemiology

33%

R

15%

Bayesian Statistics

10%

Gordon setter

7%

Painting

1%

Experience

 
 
 
 
 
McGill University
Professor (Joint Medicine and Epidemiology, Biostatistics and Occupational Helath)
McGill University
Jul 2001 – Present Montreal

Responsibilities include:

 
 
 
 
 
McGill University Health Center
Cardiologist
McGill University Health Center
Jul 2001 – Present Montreal

Responsibilities include:

Recent Publications

Additional publications - see CV

SAMPLE PUBLICATIONS

(2022). Pacemaker risk following transcatheter aortic valve replacement - A Bayesian reanalysis. International Journal of Cardiology 355 (2022) 32–36.

PDF DOI

(2021). Bayesian reanalyses of recent CV trials. Canadian Journal of Cardiology - Sept 2021.

PDF DOI

(2020). Bayesian Interpretation of the EXCEL and other RCTs. JAMA Intern Med 2020 Jun 1;e201647.

PDF DOI

(2019). Spontaneous variability of high sensitivity cardiac troponin. Canadian Journal of Cardiology 35 (2019) 1505-1512.

PDF DOI

Recent Posts

Something old and something older
I’m co-teaching a small group learning course on critical appraisal for our MPH students. We have tried to avoid the common theme of many critical appraisal courses and journal clubs that simply try to trash whatever article is under review.
Last updated on Mar 23, 2023 6 min read
Something old and something older
Absence of evidence is not evidence of absence
A previous post referred to the difficulty some researchers / reviewers have in distinguishing between absence of evidence and evidence of absence, even though this issue has been well discussed for almost 30 years (see here and here).
Last updated on Mar 20, 2023 5 min read
Absence of evidence is not evidence of absence
What does scientific authorship mean?
I recently reviewed a paper with 18 authors which reached a conclusion of no morality difference between 2 contrasts (RR 1.0, 95% CI 0.5-2.0). Now this is an obviously faulty interpretation that mixes “absence of evidence with evidence of absence”.
Last updated on Dec 6, 2022 3 min read
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Talks

Can medical guidelines adversely affect the health commons?
Presentation for the McGill Department of Medicine course entitlted “The ‘Crisis’ in Health Research, and its Implications for Research, Health Policy, and Clinical Practice”"
Apr 11, 2022 9:00 AM — 10:30 AM McGill University
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Can medical guidelines adversely affect the health commons?
Dual Antiplatelet Therapy (DAPT) in 2022
Grand rounds presentation for St. Mary’s Hospital Department of Medicine.
Feb 3, 2022 8:00 AM — 9:00 AM St. Mary's Hospital
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Dual Antiplatelet Therapy (DAPT) in 2022
Colchicine and coronary artery disease
Presentation for the annual scientific meeting of the Quebec Association of Vascular Sciences
Nov 19, 2021 12:00 PM — 1:00 PM Webinar
PDF Slides Follow
Colchicine and coronary artery disease
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Accomplish­ments

Previous accomplishments (2019 - 2020)

Accomplishments (2021)

Statistical methods for risk prediction and prognostic models
Keele University Nov 2021
Develop and validate risk prediction and prognostic models, specifically for binary or time-to-event clinical outcomes.
See certificate
Matching and Weighting for Causal Inference with R
Statistical Horizons Jan 2021
Quasi-experimental techniques of matching and weighting methods using R to estimate causal effects from observational data.
See certificate
Machine Learning
Statistical Horizons Jan 2021
Within R framework, topics included cross-validation and and advanced variable selection methods for regression analysis.
See certificate

Projects

(Mostly) Clinical Epidemiology with R
Teaching material Mar 2021
First 10 chapters of an online E book on clinical epidemiology using R, created with Bookdown (other chapters to follow).
TC4 Ticagrelor compared to clopidogrel in acute coronary syndromes - the TC4 comparative effectiveness study
Research project Sep 2019
CIHR funded project looking at the comparative effectiviness of ticagrelor versus clopidogrel in acute coronary syndromes.

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